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NFL Picks: New England Patriots Favored Over Peyton Manning, Indianapolis Colts

Published by on November 19, 2010
Article Source: Bleacher Report - Indianapolis Colts

Not surprisingly, a lot is at stake when the Indianapolis Colts meet the New England Patriots Sunday, as always seems to be the case. Though some faces have changed, Tom Brady and Peyton Manning still have their teams sitting atop their respective divisions. NFL lines for this game show us odds of Patriots minus-four over the Colts with a total set of 49 points.

These are the two winningest teams over the past decade by far, and they’ll meet in November for a sixth straight season. Indianapolis is 4-1 in the last five meetings in this series, though Tom Brady did not play in one of those games. Brady owns a 7-4 career edge in head-to-head meetings with Manning, with two of those victories coming in the playoffs.<...

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